The 23 guns he brought to the hotel room is key. It has been reported that only one was a handgun. I'm willing to wager that he committed suicide with that handgun and he brought it explicatively for that purpose. Clearly, at least one of those guns was a fully automatic machine gun, and it has been reported that he had set up two shooting platforms with tripod-mounted guns, if he had a backup gun for each shooting position, together with the handgun, we are up to five guns already. Given that each additional weapon brought up to the hotel room represented an operational risk, how could he have rationally justified the need for 23 guns for this suicidal lone-shooter operation? The only rational for 23 weapons in the room is that Stephen Paddock had a gun fetish and it played a big role in this shooting spree.
UPDATE: Tuesday 3 October 2017
According to USA Today, Marilou Danley, who is reported to be the shooter's girl friend has been out of the country and is no longer considered a "person of interest."
House Speaker Paul Ryan (R-WI) on Tuesday said Congress is focusing on “mental illness reform” to prevent mass shootings in the future
President Trump on Tuesday called Mr. Paddock “a sick man, a demented man,” adding that “we are dealing with a very, very sick individual.”
The 995 civilians killed in Syria in September are not less worthy of remembrance and mourning than the 59 killed in Las Vegas.— Linux Beach (@LinuxBeach) October 4, 2017